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Rimantadine

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  • Early treatment of disease caused by type A influenza viruses in adults and children over 10 years old. Prevention of type A influenza during an epidemic in adults and children over 10 years old.
    $15
  • Pharmacological properties Pharmacodynamics Rimantadine hydrochloride is an amantadine derivative that exhibits pronounced antiviral activity. It is effective against various influenza A viruses and also exhibits an antitoxic effect against influenza caused by the B virus. Rimantadine inhibits viral replication at early stages of the cycle by disrupting the formation of the viral envelope. Genetic studies have shown that the specific protein of the M2 gene of the virion is of great importance in the antiviral effect of rimantadine against the influenza A virus. In vitro, rimantadine inhibits the replication of all three antigenic subtypes (H1N1, H2N2, H3N3) of the influenza virus identified in humans. Rimantadine does not affect the immunogenic properties of the inactivated influenza A vaccine. Rimantadine is also effective against arboviruses, which cause tick-borne encephalitis.
    $10

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