Pharmacological properties
Pharmacodynamics. The active substance of the drug Darsil - silymarin - is obtained from the extract of the fruits of the plant milk thistle silybum marianum.
The bioactive components of silymarin neutralize free radicals in the liver, prevent the destruction of cellular structures, in particular, stabilize the membranes of hepatocytes. In damaged hepatocytes, they stimulate the synthesis of structural and functional proteins and phospholipids due to specific stimulation of RNA polymerase, prevent the loss of cell components (transaminases), and accelerate the regeneration of liver cells. They inhibit the penetration of some poisons into hepatocytes, in particular the poison of the death cap mushroom. They significantly reduce the activity of LPO in the membranes of hepatocytes, thereby strengthening them.
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